Chaomei Xiong Selected Research

protoapigenone

10/2014	A novel compound RY10-4 downregulates P-glycoprotein expression and reverses multidrug-resistant phenotype in human breast cancer MCF-7/ADR cells.
2/2014	A novel compound RY10-4 induces apoptosis and inhibits invasion via inhibiting STAT3 through ERK-, p38-dependent pathways in human lung adenocarcinoma A549 cells.
11/2012	A new protoapigenone analog RY10-4 induces apoptosis and suppresses invasion through the PI3K/Akt pathway in human breast cancer.
6/2012	RY10-4, a novel anti-tumor compound, exhibited its anti-angiogenesis activity by down-regulation of the HIF-1α and inhibition phosphorylation of AKT and mTOR.
3/2011	Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Chaomei Xiong Research Topics

Disease

8	Neoplasms (Cancer) 10/2014 - 03/2011
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2014 - 03/2011
2	Inflammation (Inflammations) 11/2014 - 06/2011
2	Edema (Dropsy) 11/2014 - 01/2012
2	Breast Neoplasms (Breast Cancer) 10/2014 - 11/2012
2	Hepatocellular Carcinoma (Hepatoma) 01/2012 - 03/2011
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 11/2014
1	Adenocarcinoma of Lung 02/2014
1	Prostatitis 01/2014
1	Fibrosis (Cirrhosis) 01/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 08/2013
1	Neuroblastoma 02/2012
1	Hemorrhage 01/2012
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2012
1	Wounds and Injuries (Trauma) 06/2011
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2011

Drug/Important Bio-Agent (IBA)

5	protoapigenoneIBA 10/2014 - 03/2011
5	FlavonoidsIBA 01/2014 - 03/2011
4	2- (1- hydroxy- 4- oxocyclohexa- 2,5- dienyl)pyran- 4- oneIBA 10/2014 - 06/2012
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014 - 03/2011
2	AcidsIBA 11/2014 - 01/2014
2	GlycosidesIBA 11/2014 - 01/2014
1	Testosterone (Sustanon)FDA Link 11/2014
1	ElementsIBA 10/2014
1	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2014
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2014
1	CarrageenanIBA 01/2014
1	CytokinesIBA 01/2014
1	2,2,2-trifluoroethyl allyl etherIBA 01/2014
1	ExilisIBA 01/2014
1	Biological ProductsIBA 08/2013
1	HydroquinonesIBA 06/2012
1	NF-kappa B (NF-kB)IBA 02/2012
1	pyrrolidine dithiocarbamic acidIBA 02/2012
1	prolinedithiocarbamate (PDTC)IBA 02/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2012
1	Pharmaceutical PreparationsIBA 01/2012
1	Puromycin AminonucleosideIBA 01/2012
1	Hypoglycemic Agents (Hypoglycemics)IBA 06/2011

Therapy/Procedure

4	Traditional Medicine (Folk Remedies) 11/2014 - 01/2012
1	Drug Therapy (Chemotherapy) 10/2014
1	Therapeutics 02/2012
1	Transplantation 01/2012